4.8 Article

Palladium-Catalyzed Direct C-H Bond Alkynylations of Heteroarenes Using gem-Dichloroalkenes

Journal

ORGANIC LETTERS
Volume 14, Issue 7, Pages 1824-1826

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol300514d

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Funding

  1. CaSuS PhD program

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Palladium-catalyzed direct alkynylations of heteroarenes were accomplished with inexpensive gem-dichloroalkenes as user-friendly electrophiles, which set the stage for a modular, step-economical synthesis of diversely decorated heteroaryl alkynes with ample scope.

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