4.8 Article

Ketone Formation via Mild Nickel-Catalyzed Reductive Coupling of Alkyl Halides with Aryl Acid Chlorides

Journal

ORGANIC LETTERS
Volume 14, Issue 12, Pages 3044-3047

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol3011198

Keywords

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Funding

  1. Chinese NSF [2097209, 21172140]
  2. Shanghai Institutions of Higher Learning Shanghai Education Committee
  3. Shanghai Leading Academic Discipline Project [S30107, J50101]

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The present work highlights unprecedented Ni-catalyzed reductive coupling of unactivated alkyl iodides with aryl acid chlorides to efficiently generate alkyl aryl ketones under mild conditions.

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