Journal
ORGANIC LETTERS
Volume 14, Issue 19, Pages 5014-5017Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol302175v
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- Regione Autonoma della Sardegna
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A one-pot synthesis of amides from aldheydes with N-chloroamines, prepared in situ from amines, has been developed. Both aliphatic and aromatic aldehydes and many types of mono- and disubstituted amines are tolerant in this transformation. This cross-coupling reaction appears simple and convenient, has a wide substrate scope and makes use of cheap, abundant, and easily available reagents.
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