4.8 Article

Rhodium(III)- and Ruthenium(II)-Catalyzed Olefination of Isoquinolones

Journal

ORGANIC LETTERS
Volume 14, Issue 16, Pages 4166-4169

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol3018352

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Funding

  1. Dalian Institute of Chemical Physics, Chinese Academy of Sciences

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NH and N-protected isoquinolones undergo Rh(III)-catalyzed oxidative olefination at the 8-position. Complementary redox-neutral olefination of such isoquinolones using internal alkynes was achieved under ruthenium catalysis.

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