4.8 Article

Ruthenium-Catalyzed Oxidative C(sp2)-H Bond Hydroxylation: Site-Selective C-O Bond Formation on Benzamides

Journal

ORGANIC LETTERS
Volume 14, Issue 16, Pages 4210-4213

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol3018819

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Funding

  1. Alexander von Humboldt Foundation

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Well-defined ruthenium carboxylate complexes enabled unprecedented ruthenium-catalyzed C(sp(2))-H hydroxylations on benzamides with PhI(OAc)(2) as the oxidant at a remarkably low catalyst loading of 1.0 mol %.

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