Journal
ORGANIC LETTERS
Volume 14, Issue 17, Pages 4594-4597Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol3020557
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Funding
- National Science Foundation of China [21172092, 20972057]
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An efficient carbo-acylation reaction of 2-arylpyridines with alpha-diketones via Pd-catalyzed C-H bond activation and C-C bond cleavage in the presence of TBHP was developed that generated aryl ketones in good yields. The highly selective formation of aryl ketones was observed when 2-arylpyridines reacted with aromatic/aliphatic alpha-diketones.
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