Journal
ORGANIC LETTERS
Volume 14, Issue 18, Pages 4766-4769Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol302031z
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Funding
- National Natural Science Foundation of China [21102071]
- Fundamental Research Funds for the Central Universities [1107020522, 1082020502]
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A catalyst-free intramolecular oxidative cyclization reaction of N-allylbenzamides has been developed to prepare 2,5-disubstituted oxazoles with good yields. This reaction gives an efficient synthetic strategy to form an oxazole nucleus directly from easily accessible substrates under temperate conditions.
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