Journal
ORGANIC LETTERS
Volume 14, Issue 14, Pages 3672-3675Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol301519m
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Funding
- National Natural Science Foundation [21072219]
- Ministry of Science and Technology of China [2009CB522302]
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Eryngiolide A (1), the first member of C20 diterpenoids with the skeleton deriving from a cyclododecane core fused with two gamma-lactone units, was isolated from the solid culture of the edible mushroom Pleurotus eryngii. The structure of 1 was elucidated by extensive analysis of NMR spectra. Compound 1 exhibited moderate cytotoxicity against two human cancer lines in vitro.
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