4.8 Article

Cytosine Derivatives Form Hemiprotonated Dimers in Solution and the Gas Phase

Journal

ORGANIC LETTERS
Volume 14, Issue 10, Pages 2560-2563

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol300861r

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Funding

  1. American Chemical Society
  2. UC Riverside
  3. NSF [CHE-0848517]
  4. Direct For Mathematical & Physical Scien [0848517] Funding Source: National Science Foundation
  5. Division Of Chemistry [0848517] Funding Source: National Science Foundation

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Hemiprotonated dimers of cytosine derivatives, implicated in the formation of the i-motif of DNA, have been created in solution and the gas phase. The mechanism of dimerization has been analyzed by mass spectrometry and multidimensional NMR spectroscopy.

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