4.8 Article

2-Pyridone Synthesis Using 2-(Phenylsulfinyl)acetamide

Journal

ORGANIC LETTERS
Volume 15, Issue 1, Pages 232-234

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol303320c

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Funding

  1. Japan Society for the Promotion of Science (JSPS) [20002004, 22590002]
  2. Research Foundation for Pharmaceutical Sciences
  3. Mochida Memorial Foundation for Medical and Pharmaceutical Research
  4. Uehara Memorial Foundation
  5. Sumitomo Foundation
  6. Grants-in-Aid for Scientific Research [22590002] Funding Source: KAKEN

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2-Pyridones were prepared by means of an efficient protocol including the 1,4-addition of 2-(phenylsulfinyl)acetamide to alpha,beta-unsaturated ketones followed by cyclization and sulfoxide elimination.

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