Journal
ORGANIC LETTERS
Volume 14, Issue 21, Pages 5416-5419Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol3026507
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Funding
- National Basic Research Program of China [973-2011CB808700]
- National Nature Science Foundation of China [20972175, 20923005, 21121062]
- Science and Technology Commission of the Shanghai Municipality [11JC1415000]
- Chinese Academy of Sciences
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A silver-catalyzed intramolecular oxidative aminofluorination of alkynes has been developed by using NFSI as a fluorinating reagent. This reaction represents an efficient method for the synthesis of various 4-fluoroisoquinolines and 4-fluoropyrrolo[alpha]isoquinolines.
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