Journal
ORGANIC LETTERS
Volume 14, Issue 11, Pages 2910-2913Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol301203z
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Funding
- Department of Pharmacology, Vanderbilt University Medical Center
- Vanderbilt Specialized Chemistry Center for Accelerated Probe Development/MLPCN [U54MH084659]
- ACS Division of Medicinal Chemistry
- NIH [S10 RR019022]
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A short, high yielding protocol has been developed for the enantioselective and general synthesis of C2-functionalized, benzyl protected morpholines and orthogonally N,N'-protected piperazines from a common intermediate.
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