4.8 Article

Synthesis of the Reported Structures for Kealiinines B and C

Journal

ORGANIC LETTERS
Volume 14, Issue 18, Pages 4734-4737

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol3019242

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Funding

  1. National Institutes of Health [R01-GM 090082, R01-CA140296]
  2. DOD [W81XWH-09-1-0431]

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Syntheses of the reported structures of kealiinines B and C have been executed. An intermolecular electrophile-induced cyclization of a pendant arene on an ene-guanidine affords the tetracyclic, oxidized naphthimidazole cores.

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