4.8 Article

Ligand-Free Ag(I)-Catalyzed Carboxylation of Terminal Alkynes with CO2

Journal

ORGANIC LETTERS
Volume 13, Issue 9, Pages 2402-2405

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol200638z

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Funding

  1. National Natural Science Foundation of China [20802007]
  2. National Basic Research Program of China (973Program) [2009CB825300]

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A convenient approach to selectively prepare a wide range of functionalized propiolic acids was developed by Agl-catalyzed carboxylation of terminal alkynes using carbon dioxide as carboxylative agent under ligand-free conditions.

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