4.8 Article

Iron-Catalyzed Cycloaddition of Alkynenitriles and Alkynes

Journal

ORGANIC LETTERS
Volume 13, Issue 11, Pages 2936-2939

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol2009939

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Funding

  1. DOE
  2. NSF
  3. NIGMS [5RO1GM076125]
  4. Direct For Mathematical & Physical Scien
  5. Division Of Chemistry [0911017] Funding Source: National Science Foundation

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The combination of Fe(OAc)(2) and an electron-donating, sterically hindered pyridyl bisimine ligand catalyzes the cycloaddition of alkynenitriles and alkynes. A variety of substituted pyridines were obtained in good yields.

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