4.8 Article

Natural Product Biosynthesis Inspired Concise and Stereoselective Synthesis of Benzopyrones and Related Scaffolds

Journal

ORGANIC LETTERS
Volume 13, Issue 8, Pages 1988-1991

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol200389p

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Funding

  1. Max Planck Gesellschaft

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A natural product biosynthesis-inspired strategy to explore biologically relevant chemical space is presented. A phosphine-catalyzed cascade and stereoselective annulation provides a common tricyclic benzopyrone intermediate that was efficiently transformed into diverse and related naturally occurring scaffolds.

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