4.8 Article

Copper-Catalyzed Aerobic Oxidative Intramolecular C-H Amination Leading to Imidazobenzimidazole Derivatives

Journal

ORGANIC LETTERS
Volume 14, Issue 2, Pages 452-455

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol202884z

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Funding

  1. National Natural Science Foundation of China [20972083, 21172128]
  2. Ministry of Science and Technology of China [2012CB722600]

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A highly efficient copper-catalyzed aerobic oxidative intramolecular C-H amination has been developed using substituted 2-(1H-imidazol-1-yl)-N-alkylbenzenamines as the starting materials, and the corresponding imidazobenzimidazole derivatives were obtained in excellent yields. This is an economical and practical method for the construction of N-heterocycles.

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