4.8 Article

Organocatalytic Enantioselective Friedel-Crafts Reactions of 1-Naphthols with Aldimines

Journal

ORGANIC LETTERS
Volume 13, Issue 5, Pages 828-831

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol102987n

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Funding

  1. University of New Mexico
  2. Thousand Talents program of China

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An organocatalytic enantioselective Friedel Crafts reaction of 1-naphthols with aldimines has been developed. The method affords a direct access to chiral aminoarylnaphthols in good yields and with good to high enantioselectivities.

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