4.8 Article

Decarbonylative Cycloaddition of Phthalic Anhydrides with Allenes

Journal

ORGANIC LETTERS
Volume 13, Issue 6, Pages 1374-1377

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol200044y

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Funding

  1. Ministry of Education, Culture, Sports, Science, and Technology, Japan
  2. Novartis Foundation
  3. Asahi Glass Foundation
  4. Kansai Research Foundation
  5. Mizuho Foundation for the Promotion of Sciences

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The decarbonylative cycloadditions of phthalic anhydrides with allenes were performed by using nickel catalyst. The asymmetric variant of the cycloaddition was also achieved by using chiral phosphine ligands to provide delta-lactones enantioselectively.

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