Journal
ORGANIC LETTERS
Volume 13, Issue 22, Pages 6066-6069Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol202552y
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- Deutsche Forschungsgemeinschaft
- Fonds der Chemischen Industrie
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The synthesis of a variety of substituted quinolines from N-alkyl anilines by a one-pot dehydrogenative Povarov/oxidation tandem reaction with mono- and 1,2-disubstituted aryl and alkyl olefins was developed. A simple protocol using cheap and benign iron(111)chloride as the Lewis acid catalyst and a TEMPO oxoammonium salt as a nontoxic, mild, efficient oxidant is reported.
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