4.8 Article

Carbon-Sulfur Bond Formation via Iridium-Catalyzed Asymmetric Allylation of Aliphatic Thiols

Journal

ORGANIC LETTERS
Volume 13, Issue 6, Pages 1514-1516

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol200197v

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Funding

  1. NSFC [20942003]
  2. Shanghai Education Committee [09ZZ36]
  3. Tongji University
  4. Key Laboratory of Fluorine Chemistry
  5. Shanghai Institute of Organic Chemistry
  6. Chinese Academy of Sciences
  7. State Key Laboratory of Fine Chemicals
  8. Dalian University of Technology [KF1006]

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An iridium-catalyzed regio- and enatioselective allylation with aliphatic thiols as the nucleophile in dichloromethane has been accomplished; and the branch products were obtained in 34-80% yields with up to 94/6 b/l and 98% ee.

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