4.8 Article

Monoalkylation of Acetonitrile by Primary Alcohols Catalyzed by Iridium Complexes

Journal

ORGANIC LETTERS
Volume 13, Issue 15, Pages 4084-4087

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol2015972

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Funding

  1. Sanofi-Aventis

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The monoalkylation of acetonitrile by primary alcohols was achieved in a one-pot sequence In the presence of iridium catalysts. A diversity of nitriles has been obtained from aryl- and alkyl-methanols in excellent yield.

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