4.8 Article

Development of the Intramolecular Prins Cyclization/Schmidt Reaction for the Construction of the Azaspiro[4,4]nonane: Application to the Formal Synthesis of (±)-Stemonamine

Journal

ORGANIC LETTERS
Volume 13, Issue 4, Pages 724-727

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol102955e

Keywords

-

Funding

  1. NSFC [20621091, 20672048, 20732002, 20972059]
  2. MOE [2010CB833200]

Ask authors/readers for more resources

A TiCl4-promoted tandem intramolecular Prins cyclization/Schmkit reaction has been designed and developed to be an efficient method for the construction of the azaspiro[4,4]nonane. The present tandem protocol has been employed to construct the tricyclic azaquaternary skeleton (ring A, B, and C) of stemonamine.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available