4.8 Article

Manganese Dioxide Catalyzed N-Alkylation of Sulfonamides and Amines with Alcohols under Air

Journal

ORGANIC LETTERS
Volume 13, Issue 23, Pages 6184-6187

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol202582c

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Funding

  1. National Natural Science Foundation of China [20902070]
  2. Natural Science Foundation [Y4100579]
  3. Qianjiang Talents Program of Zhejiang Province [QJD0902004]

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By simply running the reactions under air and solvent-free conditions using catalytic amounts of manganese dioxide, a practical and efficient N-allrylation method for a variety of sulfonamides and amines using alcohols as green alkylating reagents was developed.

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