Journal
ORGANIC LETTERS
Volume 13, Issue 20, Pages 5556-5559Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol202276h
Keywords
-
Categories
Funding
- NIGMS Centers of Excellence for Chemical Methodology and Library Development [P50 GM069721]
Ask authors/readers for more resources
An intramolecular aza-Michael reaction with a Cbz carbamate and an enone is reported to result in 3,5-disubstituted nitrogen-containing heterocycles. Either cis or trans isomers were obtained selectively using chiral substrates and an achiral Pd (II) complex or strong Bronsted acid catalysis. A range of substrates undergoes these selective transformations. Functionalization of the resulting products yielding bicyclic heterocycles is also demonstrated.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available