4.8 Article

Kinetic Resolution of β-Lactams via Enantioselective N-Acylation

Journal

ORGANIC LETTERS
Volume 13, Issue 18, Pages 4755-4757

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol201911z

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Funding

  1. National Science Foundation [CHE-1012979]

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Enantioselective N-acylation of 4-aryl-beta-lactams in the presence of acyl transfer catalyst CI-PIQ provides an effective method for their nonenzymatic kinetic resolution.

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