4.8 Article

Palladium-Catalyzed Oxidative Cross-Coupling between Pyridine N-Oxides and Indoles

Journal

ORGANIC LETTERS
Volume 13, Issue 7, Pages 1766-1769

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol200306y

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Funding

  1. Dalian Institute of Chemical Physics, Chinese Academy of Sciences
  2. NSFC [21072188]

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A Pd(II)-catalyzed oxidative coupling between pyridine N-oxides and N-substituted indoles via 2-fold C-H bond activation was achieved with high selectivity using Ag2CO3 as an oxidant.

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