4.8 Article

Addition of Arylboronic Acids to Arylpropargyl Alcohols en Route to Indenes and Quinolines

Journal

ORGANIC LETTERS
Volume 13, Issue 19, Pages 5314-5317

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol202176g

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Funding

  1. Natural Sciences and Engineering Research Council (NSERC)
  2. Merck
  3. University of Toronto

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A regio- and stereoselective rhodium-catalyzed synthesis of trisubstituted allylic alcohols is described. The utility of these synthons is demonstrated in a convenient synthesis of indenes and quinolines.

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