4.8 Article

Construction of Carbocyclic Ring of Indoles Using Ruthenium-Catalyzed Ring-Closing Olefin Metathesis

Journal

ORGANIC LETTERS
Volume 13, Issue 18, Pages 4762-4765

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol201510u

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Funding

  1. Ministry of Education, Culture, Sports, Science and Technology, Japan [KIBAN C-22550029]
  2. Grants-in-Aid for Scientific Research [22550029] Funding Source: KAKEN

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The selective synthesis of substituted indoles was achieved by the ring-closing olefin metathesis (RCM)/elimination sequence or the RCM/tautomerization sequence of functionalized pyrrole precursors. The RCM/elimination sequence was also applied to double ring closure to yield a substituted carbazole.

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