Journal
ORGANIC LETTERS
Volume 13, Issue 8, Pages 1897-1899Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol200377w
Keywords
-
Categories
Funding
- National S & T Major Project [2009ZX09301-001]
- National Marine 863 Project [2007AA09Z447, 2007AA09Z402]
- NSFC [30730108, 20721003, 20772136]
- CAS [KSX2-YW-R-18]
- STCSM [10540702900]
- MIUR
Ask authors/readers for more resources
The first chemical study of an Actinocyclidae nudibranch, Actinocyclus papillatus, resulted in the isolation of (-)-actisonitrile (1), a lipid based on a 1,3-propanediol ether skeleton. The structure was established by spectroscopic methods, whereas the absolute configuration of the chiral center was determined by comparing the optical properties of natural actisonitrile with those of (+)- and (-)-synthetic enantiomers, opportunely prepared. Both (-)- and (+)-actisonitrile were tested in preliminary in vitro cytotoxicity bioassays on tumor and nontumor mammalian cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available