4.8 Article

Synthesis and Cross-Coupling of Sulfonamidomethyltrifluoroborates

Journal

ORGANIC LETTERS
Volume 13, Issue 7, Pages 1694-1697

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol200202g

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Funding

  1. National Priorities Research Program (NRP)
  2. Qatar National Research Fund [08-035-1-008]
  3. NIH [R01 GM-081376]

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Sulfonamidomethyltrifluoroborates were successfully synthesized and cross-coupled with a wide range of aryl and heteroaryl chlorides, allowing the construction of a sulfonamidomethyl aryl linkage through a new disconnection, thus offering a new way to access such structurally interesting motifs.

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