4.8 Article

Nickel-Catalyzed Cycloadditions of Thiophthalic Anhydrides with Alkynes

Journal

ORGANIC LETTERS
Volume 13, Issue 8, Pages 1912-1915

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol200336c

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Funding

  1. Ministry of Education, Culture, Sports, Science, and Technology, Japan
  2. Asahi Glass Foundation
  3. Kansai Research Foundation for the Promotion of Science
  4. Grants-in-Aid for Scientific Research [21106005, 21106001] Funding Source: KAKEN

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Nickel-catalyzed cycloadditions have been developed where thiophthalic anhydrides react with alkynes to afford substituted sulfur-containing heterocyclic compounds. Selective formations of thioisocoumarins, benzothiophenes, and thiochromones were accomplished with three different reaction conditions.

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