Journal
ORGANIC LETTERS
Volume 13, Issue 4, Pages 696-699Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol102925d
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Funding
- KAKENHI [20611002]
- University of Tokyo
- NIEHS, DHHS [P01 ES 10594]
- MARBIONC, Marine Biotechnology in North Carolina
- SUNBOR Scholarship
- Grants-in-Aid for Scientific Research [22404006, 20611002] Funding Source: KAKEN
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The first and highly efficient total synthesis of (-)-brevisin has been achieved. The title compound was synthesized in only 29 steps (longest linear sequence) from commercially available starting materials. The synthesis provided over 70 mg of a marine polycyclic ether compound.
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