Journal
ORGANIC LETTERS
Volume 13, Issue 5, Pages 884-887Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol1029386
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- Ministry of Land, Transport and Maritime Affairs of Korea
- Ministry of Education & Human Resources Development. Republic of Korea
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Two new sesterterpenoids, phorbasones A (1) and B (2), were isolated from the Korean marine sponge Phorbas sp. Their complete structures were elucidated by spectral data and chemical reactions. Phorbasone A exhibited a positive effect on the calcium deposition activity in C3H10T1/2 cells. The biogenic origin of the core structure is believed to be through a novel rearrangement from the ansellone carbon structure.
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