4.8 Article

Palladium-Catalyzed C-H Arylation of 2,5-Substituted Pyrroles

Journal

ORGANIC LETTERS
Volume 13, Issue 2, Pages 288-291

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol102734g

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Funding

  1. U.S. Department of Energy [Office of Basic Energy Sciences] [DE-FG02-08ER 15997]
  2. Rackham graduate school

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The palladium-catalyzed direct arylation of 2,5-substituted pyrrole derivatives with diaryliodonium salts to generate tri-, tetra-, and penta-substituted pyrrole products is described. The scope and limitations of these transformations are also reported.

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