Journal
ORGANIC LETTERS
Volume 13, Issue 1, Pages 150-153Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol102745h
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Funding
- National Natural Science Foundation [30721005, 20932007]
- National Science & Technology Major Project Key New Drug Creation and Manufacturing Program of the People's Republic of China [2009ZX09301-001]
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Two new limonoids, namely aphanamolides A (1) and B (2), were isolated from the seeds of Aphanamixis polystachya. Their structures were established by spectroscopic methods. Aphanamolide A (1) featured an unprecedented carbon skeleton via the formation of a C-3-C-6 bond. Compounds 1 and 2 showed cytotoxic activity against two tumor cell lines.
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