4.8 Article

Oxidative Cyclization of 2-Arylphenols to Dibenzofurans under Pd(II)/Peroxybenzoate Catalysis

Journal

ORGANIC LETTERS
Volume 13, Issue 20, Pages 5504-5507

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol202229w

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Funding

  1. Singapore National Research Foundation [NRF-RF-2009-05]
  2. Nanyang Technological University

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2-Arylphenols undergo intramolecular C-H bond activation/C-O bond formation to afford dibenzofuran derivatives under palladium catalysis In the presence of tert-butyl peroxybenzoate as an oxidant. Kinetic isotope effect experiments indicated that C-H bond cleavage Is the rate-limiting step of the reaction.

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