4.8 Article

Unique X-ray Sheet Structure of 1,8-Bis(imidazolium) Anthracene and Its Application as a Fluorescent Probe for DNA and DNase

Journal

ORGANIC LETTERS
Volume 13, Issue 6, Pages 1314-1317

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol103166q

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Funding

  1. National Research Foundation (NRF) [20100018895, 201000-01481, 2010-0001953]
  2. WCU [R31-2008-000-10010-0]
  3. Basic Research Promotion Fund [KRF-2005-205-C00043]

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A new imidazolium anthracene derivative 1 was synthesized, and its unique X-ray crystal structure was examined. In aqueous solutions, probe 1 exhibited a selective fluorescent quenching effect only with DNA among various anions including the nucleotides investigated. This probe was further applied to monitor the activity of DNase.

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