Journal
ORGANIC LETTERS
Volume 13, Issue 12, Pages 3032-3035Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol200890r
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- MICINN [CTQ2010-14959]
- MICINN
- Ramon y Cajal contract
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The combined activity of (S)-proline and an achiral cocatalyst (a TBD-derived guanidinium salt) allow direct aldol reactions to be carried out with high diastereoselectivity and enantioselectivity under solvent-free conditions with a rather simple reaction setup where stirring is not required.
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