Journal
ORGANIC LETTERS
Volume 13, Issue 19, Pages 5224-5227Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol2021109
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Funding
- Natural Science Foundation of China [20932004, 21072093]
- National Basic Research Program of China [2007CB925103, 2011CB808600]
- Ministry of Education of China [20090091110017]
- fundamental research funds for the central universities [1103020505, 1107020526]
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An effective, regioselective C-2 arylation of imidazo[2,1-b]thiazoles catalyzed by Cu(I) has been developed. This arylation proceeded smoothly without promotion of the ligands, and various functional (22 samples) groups were well tolerated. Preliminary mechanistic studies of this arylation are also reported.
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