4.8 Article

Asymmetric Synthesis of Tertiary and Quaternary Allyl- and Crotylsilanes via the Borylation of Lithiated Carbamates

Journal

ORGANIC LETTERS
Volume 13, Issue 6, Pages 1490-1493

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol200177f

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Funding

  1. EPSRC
  2. Royal Society
  3. Queen's University
  4. IRB Barcelona
  5. MICINN
  6. EPSRC [EP/E052185/1] Funding Source: UKRI
  7. Engineering and Physical Sciences Research Council [EP/D501725/1, EP/E052185/1] Funding Source: researchfish

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Tertiary allyl- or crotylsilanes have been prepared in high er and dr via the lithiation-borylation reaction of alkyl carbamates with silaboronates. Using a related strategy, quaternary allylsilanes could be accessed in similarly high er.

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