4.8 Article

Palladium-Catalyzed 1,1-Aryloxygenation of Terminal Olefins

Journal

ORGANIC LETTERS
Volume 13, Issue 5, Pages 1076-1079

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol103121r

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Funding

  1. NIH NIGMS [R01-GM073836]

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This paper describes the 1,1-arylacetoxylation of diverse alpha-olefins using organostannanes and hypervalent iodine oxidants. The reaction provides a convergent approach for generating a C-C and a C-O bond as well as a new stereocenter in a single catalytic transformation.

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