Journal
ORGANIC LETTERS
Volume 13, Issue 24, Pages 6426-6428Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol2027224
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Funding
- National Natural Science Foundation of China [21072191]
- Guangzhou Institutes of Biomedicine and Health
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A concise total synthesis of (+/-)-minfiensine using all conventional methods and starting from commercial materials has been completed. The synthesis features a Fischer indole synthesis, a Heck alkylation of an intermediate ketone enolate, conversion of a ketone carbonyl into an epoxide, and transformation of the latter into an allylic alcohol.
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