4.8 Article

2,3-Dichloro-5,6-dicyano-1,4-benzoquinone-Catalyzed Reactions Employing MnO2 as a Stoichiometric Oxidant

Journal

ORGANIC LETTERS
Volume 12, Issue 20, Pages 4686-4689

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol102078v

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Funding

  1. National Institutes of Health, Institute of General Medicine [GM062924]

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Several oxidative reactions can be effected with MnO2 in the presence of substoichiometric quantities of DDQ. These transformations include oxidative cyclization, deprotection, and dehydrogenation reactions. The use of MnO2 as a terminal oxidant for DDQ-mediated reactions is attractive based on economical and environmental factors.

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