Journal
ORGANIC LETTERS
Volume 12, Issue 22, Pages 5096-5099Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol101978h
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- EPSRC
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The simple nickel salt NiCl2 center dot 6H(2)O catalyzes the coupling of aldoximes with amines to give secondary or tertiary amide products. The aldoxime can be prepared in situ from the corresponding aldehyde. The use of O-18-labeled oximes has allowed insight into the mechanism of this reaction.
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