Journal
ORGANIC LETTERS
Volume 12, Issue 24, Pages 5680-5683Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol102499r
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Funding
- DFG
- Ministerio de Educacion
- Eusko Jaurlaritza-Gobierno Vasco
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A catalytic enantioselective synthesis of dihydrofurans has been developed. 1,3-Dicarbonyl derivatives react with (E)-beta,beta-bromonitrostyrenes in the presence of a chiral bifunctional thiourea catalyst providing mild and efficient access to diverse polysubstituted dihydrofurans in good yields and enantioselectivities.
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