4.8 Article

Iron-Mediated Direct Suzuki-Miyaura Reaction: A New Method for the ortho-Arylation of Pyrrole and Pyridine

Journal

ORGANIC LETTERS
Volume 12, Issue 12, Pages 2694-2697

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol100838m

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Funding

  1. National Science Foundation of China [20725206, 20732004, 20772085]
  2. Program for Changjiang Scholars and Innovative Research Team in University
  3. Ministry of Education in China
  4. Scientific Fund of Sichuan Province

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The first example of an iron-mediated direct Suzuki-Miyaura reaction between N-heterocyclic compounds and arylboronic acids is described, and both electron-rich and electron-deficient heteroarenes can be successfully used for the coupling reaction.

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