Transition-Metal-Free Electrophilic Amination between Aryl Grignard Reagents and N-Chloroamines

In the presence of N,N,N,N-tetramethylethylenediamine (TMEDA) as an additive, easily prepared and handled N-chloroamines react with aryl Grignard reagents to give a variety of arylamines in good to excellent yields. Functional groups such as ester and nitrile are compatible under the reaction conditions.