4.8 Article

Chromene Lock, Thiol Key, and Mercury(II) Ion Hand: A Single Molecular Machine Recognition System

Journal

ORGANIC LETTERS
Volume 12, Issue 21, Pages 4756-4759

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol101771j

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Funding

  1. National Natural Science Foundation of China [20801032, 21072119]
  2. Shanxi Provincial Natural Science Foundation [2009021006-2]
  3. Shanxi Province Foundation for Returnee [200815]
  4. Top Young Academic Leaders of Higher Learning Institutions of Shanxi (TYAL)

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A regenerative, molecular machine-like ON-OFF-ON chemosensor based on a chromene molecule with the pyran ring OFF-ON-OFF cycle is reported for the first time. It behaves as a molecular lock that requires a thiol key to open the lock and a mercury(II) ion hand that unlatches the key for unsheathing the key to close the lock.

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