Journal
ORGANIC LETTERS
Volume 12, Issue 3, Pages 532-535Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol902720d
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- NIH NIGMS [GM-073836]
- Dupont
- AstraZeneca
- Merck
- Amgen
- Abbott
- GlaxoSmithKline
- Roche
- Eli Lilly
- Bristol Myers Squibb
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O-Acetyl oximes serve as effective directing groups for Pd-catalyzed sp(2) and sp(3) C-H functionalization reactions. The C-H functionalization products can be subsequently transformed into ortho- or beta-functionalized ketones, alcohols, amines, and heterocycles.
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